(Answered) NR507 Week 4: Open Forum Discussion

This week, we are covering Alterations in Renal and Urinary Function. As you reflect on the concepts of fluid and electrolytes and acid/base balance covered in the last two weeks, tell us one alteration that could occur in fluid and electrolyte and acid/base balance due to a renal or urinary disorder.


One of the common renal diseases is chronic kidney disease (CKD). CKD is linked to heightened risk of adverse outcomes in cardiovascular, advancement to end-stage renal disease (ESRD) and increased mortality. Kidneys play a key role in the regulation of body fluids, electrolytes as well as acid/base balance by means of reabsorbing bicarbonate filtered by the glomeruli and excretion of titratable acids and ammonia into the urine (Kraut & Madias, 2017). As such, kidney failure can result in various major alterations. One alteration that occurs in fluid and electrolyte and acid/base balance due to renal failure is metabolic acidosis. On a daily basis, the renal tubules usually reabsorb approximately 4,500 mmol filtered bicarbonate under physiological conditions (Kraut & Madias, 2017). Further, to neutralize the daily generated net acid, the renal tubules generate about 80 mEq (Kraut & Madias, 2017)….Please click the icon below to purchase full solution at $5