6415 quiz 2

Question 1
0 out of 4 points

What is the distribution alteration in the older adult that can negatively affect drug response compared to the adult?

Question 2
4 out of 4 points

Which of the following is TRUE regarding the first pass effect?

Question 3
4 out of 4 points

What alteration in pharmacokinetics causes the most adverse drug reactions with drug accumulation in the older adult?

Question 4
0 out of 4 points

What is the metabolism alteration in the infant that can negatively affect drug response compared to the adult?

Question 5
0 out of 4 points

What is the distribution alteration that can negatively affect drug response in the older adult compared to the adult?

Question 6
4 out of 4 points

Which type of drug is relatively safer?

Question 7
0 out of 4 points

The nurse practitioner is preparing to prescribe isotretinoin for a 20 year old female. Besides enrolling the client in the iPLEDGE registry, what is the next best safety intervention?

Question 8
4 out of 4 points

What is the absorption alteration in the infant that can negatively affect drug response compared to the adult?

Question 9
4 out of 4 points

Why are infants sensitive to drugs that affect CNS (central nervous system)?

Question 10
4 out of 4 points

The portion of a drug that is bound to albumin is:

Question 11
4 out of 4 points

Which of the following is TRUE about a drug’s half-life?

Question 12
4 out of 4 points

Your 83 year old client has a low serum albumin level. You are prescribing warfarin, which is a highly protein bound medication. Which of the following would you expect:

Question 13
4 out of 4 points

What weeks during gestation would drugs be most likely to cause gross malformations?

Question 14
0 out of 4 points

What is the absorption alteration that can negatively affect drug response in the older adult compared to the adult?

Question 15
4 out of 4 points

Your client is a 5 month-old infant. She was full term at delivery with no postdelivery complications. If considering prescribing for her, the prescriber knows:

Question 16
0 out of 4 points

What is an intervention to decrease transmission of drugs from nursing mother to the infant?

Question 17
4 out of 4 points

All of the following are TRUE about cytochrome p450 enzymes EXCEPT:

Question 18
4 out of 4 points

What is the most COMMON way a drug crosses a cell membrane?

Question 19
0 out of 4 points

What is the distribution alteration in the infant that can negatively affect drug response compared to the adult?

Question 20
0 out of 4 points

Which of the following is the correct definition of drug absorption?

Question 21
4 out of 4 points

Most drugs exist either as weak acids or weak bases. Which is true regarding aspirin, a weak acid?

Question 22
4 out of 4 points

Amlodipine has a half life of approximately 30 to 50 hours. The medication is dosed once per day. Assuming your client has normal metabolizing function and is compliant with the dosing regimen, how many days after initiating amlodipine therapy will the client be at steady state?

Question 23
4 out of 4 points

What is the metabolism alteration in the older adult that can negatively affect drug response compared to the adult?

Question 24
4 out of 4 points

Rifampin is an antimicrobial drug that is a CYP2C9 INDUCER.

Diazepam is a muscle relaxant drug that is a CYP2C9 SUBSTRATE.

What would be the expected interaction if these medications were administered together?

Question 25
4 out of 4 points

Albuterol binds to and ACTIVATES beta-2 receptors in the smooth muscles of bronchioles, producing bronchodilation. Albuterol would be considered a beta-2 _____________.